Collagenase SANTYL® Ointment is indicated for debriding chronic dermal ulcers and severely burned areas. Occasional slight transient erythema has been noted in surrounding tissue when applied outside the wound. One case of systemic hypersensitivity has been reported after 1 year of treatment with collagenase and cortisone.
Use of Collagenase SANTYL® Ointment should be terminated when debridement is complete and granulation tissue is well established.
See complete prescribing information for more details.
Reference: 1. Mandl I. Collagenases and elastases, In: Nord FF, ed. Advances in Enzymology. New York, NY: Interscience Publishers, Inc.; 1961: 163-264.