Proper Application Planning

Determining the Proper Quantity of Collagenase SANTYL^® Ointment

When using SANTYL^® Ointment, this guide will help you determine the proper amount to apply, based on the size of the wound.

(Not intended to supersede independent clinical judgment or institutional protocols; all values approximate)

*Wound area x application depth is assumed to be 2 mm (approximately nickel thickness); SANTYL^® Ointment density = 0.85 g/mL; wound area x application depth x 0.85 g/mL = grams per application.

Collagenase SANTYL^® Ointment is indicated for debriding chronic dermal ulcers and severely burned areas. Occasional slight transient erythema has been noted in surrounding tissue when applied outside the wound. One case of systemic hypersensitivity has been reported after 1 year of treatment with collagenase and cortisone.

^†Use of Collagenase SANTYL^® Ointment should be terminated when debridement is complete and granulation tissue is well established.