Hospital outpatient re-encounters at 180 days
* Outpatient re-encounter rate at 180 days after inpatient index visit was 26% for the SANTYL Ointment group vs 34% for the medicinal honey group (P<0.05).
† Outpatient re-encounter rate at 180 days after outpatient index visit was 63% for the SANTYL group vs 71% for the medicinal honey group (P<0.05).
|Dreyfus J, et al. (2018)23|
|Objective||Determine the proportion of PU patients treated with SANTYL Ointment or medicinal honey among inpatients and outpatients in US hospitals, and then compare hospital utilization post-discharge for both debridement methods.|
|Primary endpoint||Determine all-cause inpatient readmissions or outpatient revisits to the same hospital at 30, 60, 90, and 180 days post-index discharge date.|
Inpatients§ with PUs treated with:
Outpatients|| with PUs treated with:
US Premier Healthcare Database: Extracted hospital discharge records for patients receiving debridement and having an ICD-9 code for PU.
‡ >77% of inpatients and >74% of outpatients had Medicare health coverage. >9% of inpatients and >10% of outpatients had commercial insurance.
§ There was no significant difference in comorbidities (immobility, neuropathy, urinary incontinence, chronic kidney disease, or diabetes) between the SANTYL Ointment and medicinal honey cohorts.
|| There was no significant difference in comorbidities (immobility, neuropathy, heart failure) between the SANTYL Ointment and medicinal honey cohorts, however, the SANTYL Ointment cohort had more malnutrition, urinary incontinence, chronic kidney disease, dementia, and diabetes.
¶ Database complies with the Health Insurance Portability and Accountability Act of 1996.
Important Safety Information:Use of SANTYL Ointment should be terminated when debridement is complete and granulation tissue is well established.
One case of systemic hypersensitivity has been reported after 1 year of treatment with collagenase and cortisone. Occasional slight transient erythema has been noted in surrounding tissue when applied outside the wound.