Compared to medicinal honey users, SANTYL Ointment patients had:
* The type of episodic debridement was not specified in the data set.
In a retrospective study, pressure ulcers treated with SANTYL Ointment were found to be:
than honey to achieve 100% granulation at one year15†(P=0.018)
than honey to epithelialize at one year15‡(P=0.024)
† Granulation was defined as percentage of the wound bed with granulation tissue formed. One hundred percent granulation was defined as complete debridement of the wound bed.
‡ Epithelialization was defined as a “controlled” or “improved and not worsening” wound bed lacking exudate, with wound area <0.2cm2, and tissue depth <0.1cm.
|Gilligan A. (2017)15|
|Objective||To retrospectively compare clinical outcomes between enzymatic debridement with SANTYL Ointment and autolytic support with medicinal honey for the treatment and management of pressure ulcers.|
|Limitations||EMR data was not collected for research purposes and the diagnostic and procedural coding in the medical record was recorded by physicians to support reimbursement. Diagnoses or procedures in the EMR may have been documented incorrectly or not at all, thereby potentially introducing measurement error with respect to ICD-9-CM or CPT based variables.|
Patients with pressure ulcers treated with SANTYL Ointment also:
Important Safety Information:Use of SANTYL Ointment should be terminated when debridement is complete and granulation tissue is well established.
One case of systemic hypersensitivity has been reported after 1 year of treatment with collagenase and cortisone. Occasional slight transient erythema has been noted in surrounding tissue when applied outside the wound.