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The prevalence of chronic wounds in the United States is 2%, similar to that of heart failure4

An aging population and an increase in the prevalence of diabetes has led to a rise in chronic wounds, notably DFUs.5,6 It is estimated that there are over 800,000 people affected by diabetic foot ulcers (DFUs) each year in the United States.6 In total, 6.5 million patients are affected by chronic wounds.5,7

Chronic wounds typically take longer to heal than other types of wounds and often develop complications such as infection.7,8 Debridement is an essential component of proper chronic wound care.9

The estimated impact of chronic wounds on the US health system5


6.5 million chronic wounds*

*Combined prevalence of venous ulcers, diabetic foot ulcers, and pressure ulcers

Annual direct cost (USD)

>$25 billion

Average cost per wound (USD)

~$7,500 to $70,000 to treat

Cost of venous ulcers, diabetic foot ulcers, and pressure ulcers

Additional economic burdens
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Difficult-to-heal chronic wounds create additional costs

Additional costs of chronic wounds escalate when there are complications such as additional therapy, hospitalization, infections that require IV medications, advanced treatments, and sometimes amputation.4,5

Many hospitals are unaware of the added costs of wound care5

~3x longer stays10

for patients with pressure ulcers as compared to hospitalizations with no diagnosis of pressure ulcers

1-in-5 patients11‡

readmitted within 30 days also have necrotic tissue present

~11 average days12

increase in length of stay when patient develops pressure ulcer

In the study, the readmission could have been for any reason; the readmission was not necessarily related to the wound, though it could have been.

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What's next?

The healing process

Important Safety Information:Use of SANTYL Ointment should be terminated when debridement is complete and granulation tissue is well established.

One case of systemic hypersensitivity has been reported after 1 year of treatment with collagenase and cortisone. Occasional slight transient erythema has been noted in surrounding tissue when applied outside the wound.