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Simple at-home application for patients

Moisture balance

  • Wounds with sufficient moisture will naturally activate collagenase enzyme
  • Wounds heal better in a moist environment
  • Nerve endings are protected by moisture

Edge to edge

  • Apply SANTYL Ointment out to the edges of the wound
  • New epithelial and granulation tissue grows from the wound’s edges
  • Take care not to extend beyond the wound surface although it does not harm healthy tissue

Nickel thickness

  • Apply once daily at 2mm thickness or about the thickness of a nickel

Daily dressing change

  • Daily dressing changes help remove necrotic burden from wound area to help advance the healing process
  • Moisturize cover dressing with saline if wound is dry and there is no sufficient exudate
  • The enzymatic action of SANTYL Ointment may be decreased by dressings containing iodine (I2) and some, but not all, dressings containing silver (Ag)
Compatibility with other products

SANTYL Ointment has been tested with cleansers, antimicrobial formulations, and silver dressings21

SANTYL Ointment is compatible with:

  • Products that contain alkali metal salts (ie, sodium [Na] or potassium [K]) and earth alkaline metal salts (ie, calcium [Ca] or magnesium [Mg])
  • Large non-ionic compounds and non-charged surfactant molecules
  • Antimicrobial formulations
  • Wound cleansers containing large block co-polymer surfactants (eg, poloxamers) or formulas with dilute sodium hypochlorite

The enzymatic action of SANTYL Ointment is decreased by:

  • Dressings containing iodine (I2) and some, but not all, dressings containing silver (Ag)
  • Wound cleansers designated to remove impurities, bacteria, and debris
  • Antifungal agents and products containing EDTA

For best results:

When using antibiotic powder for infection, apply prior to SANTYL Ointment. If infection persists, discontinue SANTYL Ointment until infection is controlled.

Sample set of products compatible with SANTYL Ointment21

Compatible
Silver dressings Aquacel™ Ag
ALLEVYN Ag
Iodine dressings IODOFORM™
Various other dressings Hydrofera™
Wound cleansers PROSHIELD
Anasept® Spray
Microcyn™ Rx Spray
¼-strength Dakin’s solution
Antimicrobials Mafenide Acetate
Mupirocin
Compatible
Silver dressings
Aqyacel™ Ag
ALLEVYN
Iodine dressings
IODOFORM™
Various other dressings
Hydrofera™
PROSHIELD®
Wound cleansers
Anasept® Spray
Microcyn™ Rx Spray
¼-strength Dakin’s solution
Antimicrobials
Mafenide Acetate
Mupirocin

Study did not evaluate efficacy. Study only evaluated compatibility of each product with SANTYL Ointment.

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Application

See how to apply SANTYL Ointment

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Help with savings and reimbursement

Important Safety Information:Use of SANTYL Ointment should be terminated when debridement is complete and granulation tissue is well established.

One case of systemic hypersensitivity has been reported after 1 year of treatment with collagenase and cortisone. Occasional slight transient erythema has been noted in surrounding tissue when applied outside the wound.